Dietary Salt Impairs the Endothelial Glycocalyx: The Most Important Cardiovascular Disease Risk Factor You May Never Have Heard About

Frequently, important physiological discoveries made by scientists who study obscure topics escape the attention of the general public, health professionals, and even other scientists.  Such has been the case for the endothelial glycocalyx: a delicate and fragile structure lining the inside surface of all blood vessels. The endothelial glycocalyx had been inferred from blood flow measurements as far back as the 1940’s, but due to its fragile configuration the structure had never been viewed until 1966 when it was first detected with an electron microscope using special staining procedures (1).  Over the next 30 years, scientists speculated about the function…

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