Blood vessel cells implicated in chronic inflammation of obesity

When fat cells in the body are stuffed with excess fat, the surrounding tissue becomes inflamed. That chronic, low-level inflammation is one of the driving factors behind many of the diseases associated with obesity. Now, scientists have discovered a type of cell responsible, at least in mice, for triggering this inflammation in fat tissue. Their findings could eventually lead to new ways to treat obesity.

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Blood vessel cells implicated in chronic inflammation of obesity

When fat cells in the body are stuffed with excess fat, the surrounding tissue becomes inflamed. That chronic, low-level inflammation is one of the driving factors behind many of the diseases associated with obesity. Now, scientists have discovered a type of cell responsible, at least in mice, for triggering this inflammation in fat tissue. Their findings could eventually lead to new ways to treat obesity.

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New drug combination could improve glucose and weight control in diabetes

Scientists have shown that adding an experimental cancer drug to a widely used diabetes treatment improves blood glucose control and weight loss in mice, according to a new study.

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New drug combination could improve glucose and weight control in diabetes

Scientists have shown that adding an experimental cancer drug to a widely used diabetes treatment improves blood glucose control and weight loss in mice, according to a new study.

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Drinking milk while breastfeeding may reduce the child's food allergy risk

Children of mothers who drink relatively more cow's milk during breastfeeding are at reduced risk of developing food allergies.

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Drinking milk while breastfeeding may reduce the child's food allergy risk

Children of mothers who drink relatively more cow's milk during breastfeeding are at reduced risk of developing food allergies.

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Long non-coding RNA may play a key role in cardiovascular disease

Through utilization of genetically modified high-risk atherosclerotic mice, researchers have identified and characterized Macrophage-Associated Atherosclerosis lncRNA Sequence (MAARS), which is expressed specifically in macrophages in atherosclerotic plaques and contributes to the progression of the disease.

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Long non-coding RNA may play a key role in cardiovascular disease

Through utilization of genetically modified high-risk atherosclerotic mice, researchers have identified and characterized Macrophage-Associated Atherosclerosis lncRNA Sequence (MAARS), which is expressed specifically in macrophages in atherosclerotic plaques and contributes to the progression of the disease.

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Talking to kids about weight: What the internet says and why researchers are wary

Researchers systematically reviewed numerous independently published guidelines for having conversations with children about weight status to analyze their content, consistency, actionability and scientific support. They recommend future guidelines unify their messages and be better supported by scholarly data.

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Talking to kids about weight: What the internet says and why researchers are wary

Researchers systematically reviewed numerous independently published guidelines for having conversations with children about weight status to analyze their content, consistency, actionability and scientific support. They recommend future guidelines unify their messages and be better supported by scholarly data.

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Maternal diet during lactation shapes functional abilities of milk bacteria

The mother's diet while breastfeeding can shape the profile of human milk oligosaccharides (HMO), a type of complex carbohydrate in the mother's milk. Changing the HMOs, which are food and fodder for healthy microbes, in turn modifies the functional abilities of the milk microbiome.

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Maternal diet during lactation shapes functional abilities of milk bacteria

The mother's diet while breastfeeding can shape the profile of human milk oligosaccharides (HMO), a type of complex carbohydrate in the mother's milk. Changing the HMOs, which are food and fodder for healthy microbes, in turn modifies the functional abilities of the milk microbiome.

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Three pillars of mental health: Good sleep, exercise, raw fruits and veggies

Getting good quality sleep, exercising, and eating more raw fruits and vegetables predicts better mental health and well-being in young adults, a study has found.

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Lipid identified in human breast milk may play important role in early childhood weight

A lipid metabolite called 12,13-diHOME is in human breast milk. The authors of the study propose that 12,13-diHOME, as well as linked pathway metabolites from breast milk, have a protective effect against obesity development in offspring. They also suggest that a single bout of maternal exercise may boost levels of the metabolite in breast milk and that may translate into benefits for offspring in terms of healthy growth and development.

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Three pillars of mental health: Good sleep, exercise, raw fruits and veggies

Getting good quality sleep, exercising, and eating more raw fruits and vegetables predicts better mental health and well-being in young adults, a study has found.

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Lipid identified in human breast milk may play important role in early childhood weight

A lipid metabolite called 12,13-diHOME is in human breast milk. The authors of the study propose that 12,13-diHOME, as well as linked pathway metabolites from breast milk, have a protective effect against obesity development in offspring. They also suggest that a single bout of maternal exercise may boost levels of the metabolite in breast milk and that may translate into benefits for offspring in terms of healthy growth and development.

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An avocado a day keeps your gut microbes happy, study shows

Eating avocado as part of your daily diet can help improve gut health, a new study shows. Avocados are a healthy food that is high in dietary fiber and monounsaturated fat. However, it was not clear how avocados impact the microbes in the gastrointestinal system or 'gut.'

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An avocado a day keeps your gut microbes happy, study shows

Eating avocado as part of your daily diet can help improve gut health, a new study shows. Avocados are a healthy food that is high in dietary fiber and monounsaturated fat. However, it was not clear how avocados impact the microbes in the gastrointestinal system or 'gut.'

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Does sharing health data help maintain weight loss?

Research suggests that health counselors having access to self-monitored health data would improve a person's weight loss maintenance.

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Does sharing health data help maintain weight loss?

Research suggests that health counselors having access to self-monitored health data would improve a person's weight loss maintenance.

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Carrots are healthy, but active enzyme unlocks full benefits

Carrots are a good source of beta-carotene, which is a precursor of vitamin A. But to get the full health benefits of this superfood, you need an active enzyme to produce this vitamin.

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Carrots are healthy, but active enzyme unlocks full benefits

Carrots are a good source of beta-carotene, which is a precursor of vitamin A. But to get the full health benefits of this superfood, you need an active enzyme to produce this vitamin.

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Different forms of sugar impact hunger-suppressing hormones in young adults

Drinks with sucrose compared to glucose may cause young adults to produce lower levels of appetite-regulating hormones, according to a new study.

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Different forms of sugar impact hunger-suppressing hormones in young adults

Drinks with sucrose compared to glucose may cause young adults to produce lower levels of appetite-regulating hormones, according to a new study.

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Kids gain weight when new convenience stores open nearby

A new study found that changes in the food environment around low-income and high-ethnic/racial minority populations over time impact childhood obesity. Increased availability of small grocery stores selling a selection of healthy items in close proximity to children's homes improves their weight status over time, whereas increased availability of convenience stores selling predominantly unhealthy foods is likely to be detrimental.

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Kids gain weight when new convenience stores open nearby

A new study found that changes in the food environment around low-income and high-ethnic/racial minority populations over time impact childhood obesity. Increased availability of small grocery stores selling a selection of healthy items in close proximity to children's homes improves their weight status over time, whereas increased availability of convenience stores selling predominantly unhealthy foods is likely to be detrimental.

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Exercise may protect bone health after weight loss surgery

Although weight loss surgery is a highly effective treatment for obesity, it can be detrimental to bone health. A new study suggests that exercise may help address this shortcoming.

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Exercise may protect bone health after weight loss surgery

Although weight loss surgery is a highly effective treatment for obesity, it can be detrimental to bone health. A new study suggests that exercise may help address this shortcoming.

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Obesity impairs immune cell function, accelerates tumor growth

New study in mice finds that a high-fat diet allows cancer cells to outcompete immune cells for fuel, impairing immune function and accelerating tumor growth. Cancer cells do so by rewiring their metabolisms to increase fat consumption. Blocking this rewiring enhances anti-tumor immunity. Findings suggest new strategies to target cancer metabolism, improve immunotherapies.

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Obesity impairs immune cell function, accelerates tumor growth

New study in mice finds that a high-fat diet allows cancer cells to outcompete immune cells for fuel, impairing immune function and accelerating tumor growth. Cancer cells do so by rewiring their metabolisms to increase fat consumption. Blocking this rewiring enhances anti-tumor immunity. Findings suggest new strategies to target cancer metabolism, improve immunotherapies.

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How poor oral hygiene may result in metabolic syndrome

Researchers have identified a novel mechanism by which periodontal disease may cause metabolic syndrome. By studying patients with metabolic syndrome, the researchers demonstrated high antibody titers against Porphyromonas gingivalis, the bacterium causing periodontal disease. In a mouse model, the researchers then showed that infection with this bacterium causes systemic insulin resistance and metabolic dysfunction in skeletal muscle by altering the gut microbiome. This study shows the effect periodontal disease can have on the entire body.

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How poor oral hygiene may result in metabolic syndrome

Researchers have identified a novel mechanism by which periodontal disease may cause metabolic syndrome. By studying patients with metabolic syndrome, the researchers demonstrated high antibody titers against Porphyromonas gingivalis, the bacterium causing periodontal disease. In a mouse model, the researchers then showed that infection with this bacterium causes systemic insulin resistance and metabolic dysfunction in skeletal muscle by altering the gut microbiome. This study shows the effect periodontal disease can have on the entire body.

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Replacing red meat with plant foods may reduce the risk of heart disease

Replacing red meat with high quality plant foods such as beans, nuts, or soy may be associated with a modestly reduced risk of coronary heart disease (CHD), suggests a new study.

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Replacing red meat with plant foods may reduce the risk of heart disease

Replacing red meat with high quality plant foods such as beans, nuts, or soy may be associated with a modestly reduced risk of coronary heart disease (CHD), suggests a new study.

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Blackcurrants are favorable for glucose metabolism

Blackcurrants have a beneficial effect on post-meal glucose response, and the required portion size is much smaller than previously thought, a new study shows.

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Blackcurrants are favorable for glucose metabolism

Blackcurrants have a beneficial effect on post-meal glucose response, and the required portion size is much smaller than previously thought, a new study shows.

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Healthy muscles are a carrot on a string for healthy lungs

Scientists show effectiveness of carrot-based Japanese herbal medicine called 'Ninjin'yoeito' in improving muscle atrophy in the hind legs of mice exposed to cigarette smoke, positioning the medicine as a potential treatment for sarcopenia frailty-related complications with chronic obstructive pulmonary disease (COPD).

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Healthy muscles are a carrot on a string for healthy lungs

Scientists show effectiveness of carrot-based Japanese herbal medicine called 'Ninjin'yoeito' in improving muscle atrophy in the hind legs of mice exposed to cigarette smoke, positioning the medicine as a potential treatment for sarcopenia frailty-related complications with chronic obstructive pulmonary disease (COPD).

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Lab results don't explain 'obesity paradox,' but bias may

Results of standard laboratory tests performed on adult outpatients to provide an overall picture of their health are fairly consistent between those with obesity and their leaner counterparts, investigators report.

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Lab results don't explain 'obesity paradox,' but bias may

Results of standard laboratory tests performed on adult outpatients to provide an overall picture of their health are fairly consistent between those with obesity and their leaner counterparts, investigators report.

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Eating dried fruit may be linked with better diet quality and health markers

New research found that people who ate dried fruit were generally healthier than those who did not, and on days when people ate dried fruit they consumed greater amounts of some key nutrients than on days when they skipped. However, they also found that people consumed more total calories on days when they ate dried fruit.

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Eating dried fruit may be linked with better diet quality and health markers

New research found that people who ate dried fruit were generally healthier than those who did not, and on days when people ate dried fruit they consumed greater amounts of some key nutrients than on days when they skipped. However, they also found that people consumed more total calories on days when they ate dried fruit.

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Gut microbes: a key to normal sleep

Researchers used a cocktail of antibiotics to deplete gut microbes in mice. They found that metabolites in the gut differed in these mice compared with controls. In particular, metabolic pathways involved in making important neurotransmitters like serotonin were affected. Additionally, these mice showed abnormal day-night distribution in sleep/wake patterns, particularly the amount of REM sleep, and frequent transitions between REM and non-REM sleep episodes.

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Gut microbes: a key to normal sleep

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Research shows bariatric surgery may reduce severity of COVID-19 in patients with obesity

A new study shows that among patients who have obesity and who tested positive for COVID-19, a past history of bariatric surgery was significantly associated with a lower risk of hospital and intensive care unit admission.

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Research shows bariatric surgery may reduce severity of COVID-19 in patients with obesity

A new study shows that among patients who have obesity and who tested positive for COVID-19, a past history of bariatric surgery was significantly associated with a lower risk of hospital and intensive care unit admission.

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Obesity is not only the individual's responsibility

Analysis of survey results has revealed that in women, obesity is linked to various social and economic factors. In addition, this study is the first in Japan to illuminate the connection between abuse during childhood and obesity in adulthood. These results highlight the importance of taking these factors into account when implementing policies to tackle obesity.

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Obesity is not only the individual's responsibility

Analysis of survey results has revealed that in women, obesity is linked to various social and economic factors. In addition, this study is the first in Japan to illuminate the connection between abuse during childhood and obesity in adulthood. These results highlight the importance of taking these factors into account when implementing policies to tackle obesity.

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Popular weight-loss surgery in teenagers weakens bones

A common weight loss surgery for adolescents with obesity called sleeve gastrectomy has harmful effects on bones, according to a new study.

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