Melanoma mutation rewires cell metabolism

A mutation found in most melanomas rewires cancer cells' metabolism, making them dependent on a ketogenesis enzyme. The finding points to possible strategies for countering resistance to existing drugs that target the B-raf V600E mutation, or potential alternatives to those drugs. It may also explain why the V600E mutation in particular is so common in melanomas.

from Diet and Weight Loss News -- ScienceDaily http://ift.tt/1M7IeRU

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