A novel therapy ameliorates obesity and Type 2 diabetes in mice fed a high-fat diet

A novel therapy ameliorates obesity and Type 2 diabetes in mice fed a high-fat diet. The therapy acts through sustained release of nitric oxide, a gaseous signaling chemical whose most important function in the body is relaxing the inner muscles of blood vessels.

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A novel therapy ameliorates obesity and Type 2 diabetes in mice fed a high-fat diet

A novel therapy ameliorates obesity and Type 2 diabetes in mice fed a high-fat diet. The therapy acts through sustained release of nitric oxide, a gaseous signaling chemical whose most important function in the body is relaxing the inner muscles of blood vessels.

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Gut microbiome may alter response to cancer therapy

A new study captures the current understanding of the connection between the gut microbiome and therapeutic response to immunotherapy, chemotherapy, cancer surgery and more, pointing to ways that the microbiome could be targeted to improve treatment.

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Gut microbiome may alter response to cancer therapy

A new study captures the current understanding of the connection between the gut microbiome and therapeutic response to immunotherapy, chemotherapy, cancer surgery and more, pointing to ways that the microbiome could be targeted to improve treatment.

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Poor diet associated with increased diabetes risk across all gradients of genetic risk

Genetic risk factors and diet quality are independently associated with type 2 diabetes; a healthy diet is linked to lower diabetes risk across all levels of genetic risk. That's the conclusion of a study of more than 35,000 U.S. adults.

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Living near fast food restaurants in South Asia may increase risk of Type 2 diabetes

Globally, the prevalence of type 2 diabetes mellitus is increasing. A new study suggests that living near fast food restaurants increases the risk of developing Type 2 diabetes.

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Lipidomics provides new biomarkers for cardiovascular disease and Type 2 diabetes

Using lipidomics, a modern analytical method, researchers identified those lipids that are statistically associated with cardiovascular disease and type 2 diabetes. In addition, the scientists found that a diet with an increased proportion of unsaturated fatty acids leads to a reduction in risk-associated lipids and an increase in low-risk lipids.

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Lipidomics provides new biomarkers for cardiovascular disease and Type 2 diabetes

Using lipidomics, a modern analytical method, researchers identified those lipids that are statistically associated with cardiovascular disease and type 2 diabetes. In addition, the scientists found that a diet with an increased proportion of unsaturated fatty acids leads to a reduction in risk-associated lipids and an increase in low-risk lipids.

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Scientists identify genetic variants linked to mobility changes in aging

Genetic variants in an enzyme that is important to mitochondrial function may contribute to whether individuals maintain or lose strength and mobility as they age.

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Scientists identify genetic variants linked to mobility changes in aging

Genetic variants in an enzyme that is important to mitochondrial function may contribute to whether individuals maintain or lose strength and mobility as they age.

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Boys are more demanding than girls before they are born, according to scientists

Finding out the sex of a baby during pregnancy could lead to better life chances, a new study has discovered. Male baby pregnancies are more likely to result in complications, possibly because they grow faster in the womb and require more nutrients and oxygen than supplied by the mother through the placenta -- the temporary organ that attaches to the wall of the uterus during pregnancy to help the fetus grow and develop.

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Boys are more demanding than girls before they are born, according to scientists

Finding out the sex of a baby during pregnancy could lead to better life chances, a new study has discovered. Male baby pregnancies are more likely to result in complications, possibly because they grow faster in the womb and require more nutrients and oxygen than supplied by the mother through the placenta -- the temporary organ that attaches to the wall of the uterus during pregnancy to help the fetus grow and develop.

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Humans possess surprising nutritional intelligence

Pioneering research has shed new light on what drives people's basic food preferences, indicating our choices may be smarter than previously thought and influenced by the specific nutrients, as opposed to just calories, we need.

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Humans possess surprising nutritional intelligence

Pioneering research has shed new light on what drives people's basic food preferences, indicating our choices may be smarter than previously thought and influenced by the specific nutrients, as opposed to just calories, we need.

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Automated nutrition app can help people follow healthier diet

People could benefit from fully automated personal nutritional advice, as a new research paper shows that an app improved healthy diet in clinical trials.

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Automated nutrition app can help people follow healthier diet

People could benefit from fully automated personal nutritional advice, as a new research paper shows that an app improved healthy diet in clinical trials.

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Intense exercise while dieting may reduce cravings for fatty food

In a study that offers hope for human dieters, rats on a 30-day diet who exercised intensely resisted cues for favored, high-fat food pellets. The experiment was designed to test resistance to the phenomenon known as 'incubation of craving,' meaning the longer a desired substance is denied, the harder it is to ignore signals for it. The findings suggest that exercise modulated how hard the rats were willing to work for cues associated with the pellets, reflecting how much they craved them.

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Intense exercise while dieting may reduce cravings for fatty food

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Got food cravings? What's living in your gut may be responsible

New research on mice shows for the first time that the microbes in animals' guts influence what they choose to eat, making substances that prompt cravings for different kinds of foods.

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Got food cravings? What's living in your gut may be responsible

New research on mice shows for the first time that the microbes in animals' guts influence what they choose to eat, making substances that prompt cravings for different kinds of foods.

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Ubiquitous nutrients suppress appetite and promote movement

In experiments on mice, researchers show that non-essential amino acids act as appetite suppressants and promote the urge to move. Their research provides insight into the neural mechanism that controls this behavior.

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Ubiquitous nutrients suppress appetite and promote movement

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Following a Mediterranean-style diet during pregnancy may reduce the risk of preeclampsia

An analysis of health and dietary data for more than 8,500 pregnant women found that greater adherence to a Mediterranean-style eating plan was associated with a lower risk of preeclampsia, which is a pregnancy complication characterized by severe high blood pressure that can be serious or even fatal for both mother and child. The reduction in risk of preeclampsia was greatest among Black women -- a population at high risk for preeclampsia.

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Following a Mediterranean-style diet during pregnancy may reduce the risk of preeclampsia

An analysis of health and dietary data for more than 8,500 pregnant women found that greater adherence to a Mediterranean-style eating plan was associated with a lower risk of preeclampsia, which is a pregnancy complication characterized by severe high blood pressure that can be serious or even fatal for both mother and child. The reduction in risk of preeclampsia was greatest among Black women -- a population at high risk for preeclampsia.

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Bioengineers visualize fat storage in fruit flies

A new visualization technique is being used to untangle often discussed, yet mysterious, links between diet and things like obesity, diabetes and aging.

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Bioengineers visualize fat storage in fruit flies

A new visualization technique is being used to untangle often discussed, yet mysterious, links between diet and things like obesity, diabetes and aging.

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Biologists find new protective factor against excessive lipid accumulation in liver of obese mouse

Non-alcoholic fatty liver disease (NAFLD), commonly known as fatty liver disease, is a prevalent disease frequently seen in obese people. Having high fat content in the liver is detrimental as it is strongly associated with severe health problems like diabetes, high blood pressure, and liver cancer. A research team uncovers a new protective mechanism against this disorder.

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Genes can affect our nutrient tolerance

A new study finds that minor genetic differences can affect the ability to utilize the energy of various nutrients. This work shows how nutritional planning based on genetic data could promote the development of personalized nutrition for health.

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Biologists find new protective factor against excessive lipid accumulation in liver of obese mouse

Non-alcoholic fatty liver disease (NAFLD), commonly known as fatty liver disease, is a prevalent disease frequently seen in obese people. Having high fat content in the liver is detrimental as it is strongly associated with severe health problems like diabetes, high blood pressure, and liver cancer. A research team uncovers a new protective mechanism against this disorder.

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Genes can affect our nutrient tolerance

A new study finds that minor genetic differences can affect the ability to utilize the energy of various nutrients. This work shows how nutritional planning based on genetic data could promote the development of personalized nutrition for health.

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Methionine restriction may improve aggressive brain cancer prognosis in children

Deadly brain cancers called diffuse midline gliomas are uniquely dependent on methionine, an amino acid abundant in legumes and poultry.

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Methionine restriction may improve aggressive brain cancer prognosis in children

Deadly brain cancers called diffuse midline gliomas are uniquely dependent on methionine, an amino acid abundant in legumes and poultry.

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Exercise during pregnancy reduces the risk of Type-2 Diabetes in offspring

Exercising during pregnancy bestows a wealth of benefits upon a child. New research suggests that exercise may also help reduce the offspring's chances of getting type 2 diabetes. Researchers uncovered how SOD3, a key protein released by the placenta after exercise, improves the metabolic health of offspring and negates the impacts of maternal obesity and poor diets.

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Exercise during pregnancy reduces the risk of Type-2 Diabetes in offspring

Exercising during pregnancy bestows a wealth of benefits upon a child. New research suggests that exercise may also help reduce the offspring's chances of getting type 2 diabetes. Researchers uncovered how SOD3, a key protein released by the placenta after exercise, improves the metabolic health of offspring and negates the impacts of maternal obesity and poor diets.

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About 1 in 4 adults has an often-missed liver disorder linked to higher heart disease risk

It is estimated that about one in four adults worldwide has an abnormal build-up of fat in the liver, called non-alcoholic fatty liver disease (NAFLD). NAFLD can lead to permanent liver damage, and heart disease is the leading cause of death in people with fatty liver disease. Because NAFLD is often missed in routine medical screening, the new scientific statement raises awareness and understanding about its link to heart disease and to outline how to prevent and diagnose the condition.

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About 1 in 4 adults has an often-missed liver disorder linked to higher heart disease risk

It is estimated that about one in four adults worldwide has an abnormal build-up of fat in the liver, called non-alcoholic fatty liver disease (NAFLD). NAFLD can lead to permanent liver damage, and heart disease is the leading cause of death in people with fatty liver disease. Because NAFLD is often missed in routine medical screening, the new scientific statement raises awareness and understanding about its link to heart disease and to outline how to prevent and diagnose the condition.

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Study helps explain how xanthan gum, a common food additive, is processed in the gut

A new study examines the ability of the human gut microbiome to digest xanthan gum, a relatively recently introduced food ingredient found in many processed foods.

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Study helps explain how xanthan gum, a common food additive, is processed in the gut

A new study examines the ability of the human gut microbiome to digest xanthan gum, a relatively recently introduced food ingredient found in many processed foods.

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High cardiovascular risk is associated with symptoms of depression

Cardiovascular risk factors are associated with an increased risk of depression in older adults, according to a new study.

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Concussion worse if fighters rapidly cut weight before boxing and MMA matches

Fighters who rapidly cut weight before bouts are at a higher risk of suffering concussions or being misdiagnosed with head trauma, researchers have revealed for the first time. More than 60 per cent of athletes in combat sports like boxing and mixed martial arts (MMA) revealed their symptoms were worse after dehydrating themselves to make stringent weight classes before contests.

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Concussion worse if fighters rapidly cut weight before boxing and MMA matches

Fighters who rapidly cut weight before bouts are at a higher risk of suffering concussions or being misdiagnosed with head trauma, researchers have revealed for the first time. More than 60 per cent of athletes in combat sports like boxing and mixed martial arts (MMA) revealed their symptoms were worse after dehydrating themselves to make stringent weight classes before contests.

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Obesity significantly increased heart failure risk among women with late menopause

While women who enter menopause before age 45 are known to be at higher risk of heart failure, obesity significantly increased heart failure risk among women who experienced late menopause -- at age 55 or older, according to a new study. The findings indicate that maintaining a healthy weight and avoiding abdominal obesity may protect against developing heart failure, especially among women who experience late menopause.

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Obesity significantly increased heart failure risk among women with late menopause

While women who enter menopause before age 45 are known to be at higher risk of heart failure, obesity significantly increased heart failure risk among women who experienced late menopause -- at age 55 or older, according to a new study. The findings indicate that maintaining a healthy weight and avoiding abdominal obesity may protect against developing heart failure, especially among women who experience late menopause.

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Researchers have uncovered a regulator of body weight that could lead to new treatments for metabolic disorders

Scientists uncover key regulator of body weight. They have discovered that a protein known as augmentor-alpha regulates body weight in mice, an insight that could lead to new treatments for metabolic disorders.

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Researchers have uncovered a regulator of body weight that could lead to new treatments for metabolic disorders

Scientists uncover key regulator of body weight. They have discovered that a protein known as augmentor-alpha regulates body weight in mice, an insight that could lead to new treatments for metabolic disorders.

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Researchers identify a new treatment for metabolic syndrome

Metabolic syndrome increases a person's risk for diabetes, heart disease, and stroke, and includes conditions such as obesity, high blood pressure and high blood sugar. In a recent mouse-model study researchers have furthered their progress to develop a drug to treat metabolic syndrome by identifying a receptor that controls appetite and body weight.

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Researchers identify a new treatment for metabolic syndrome

Metabolic syndrome increases a person's risk for diabetes, heart disease, and stroke, and includes conditions such as obesity, high blood pressure and high blood sugar. In a recent mouse-model study researchers have furthered their progress to develop a drug to treat metabolic syndrome by identifying a receptor that controls appetite and body weight.

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New study reveals that healthy plant-based diets are associated with a lower risk of developing diabetes

New research finds that the consumption of healthy plant-based foods, including fruits, vegetables, nuts, coffee, and legumes, is associated with a lower risk of developing type 2 diabetes (T2D) in generally healthy people and support their role in diabetes prevention.

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New study reveals that healthy plant-based diets are associated with a lower risk of developing diabetes

New research finds that the consumption of healthy plant-based foods, including fruits, vegetables, nuts, coffee, and legumes, is associated with a lower risk of developing type 2 diabetes (T2D) in generally healthy people and support their role in diabetes prevention.

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Boosting liver mRNAs curbs appetite, body weight in obese mice

Inhibiting a liver enzyme in obese mice showed promising results including reduced appetite and weight loss after 12 weeks of therapy, scientists have reported. The study points to a potential new avenue to intervene in metabolic diseases.

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Boosting liver mRNAs curbs appetite, body weight in obese mice

Inhibiting a liver enzyme in obese mice showed promising results including reduced appetite and weight loss after 12 weeks of therapy, scientists have reported. The study points to a potential new avenue to intervene in metabolic diseases.

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Kisspeptin: A new drug to treat liver disease?

A hormone that triggers puberty and controls fertility in humans might be developed as a treatment for non-alcoholic fatty liver disease, according to new Rutgers research.

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