How foodborne diseases protect the gut's nervous system

Prior infections appear to shield enteric neurons, preventing these key components of the body's 'second brain' from dying off when future pathogens strike.

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How foodborne diseases protect the gut's nervous system

Prior infections appear to shield enteric neurons, preventing these key components of the body's 'second brain' from dying off when future pathogens strike.

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Fat cells found to play a central role in cognitive decline and neurodegeneration

New findings show that fat cells control the systemic response to brain function, causing impairment in memory and cognition in mice. The activation of Na,K-ATPase oxidant amplification loop affects the expression of important protein markers in fat cells as well as in the hippocampus, which can worsen brain function and lead to neurodegeneration.

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Fat cells found to play a central role in cognitive decline and neurodegeneration

New findings show that fat cells control the systemic response to brain function, causing impairment in memory and cognition in mice. The activation of Na,K-ATPase oxidant amplification loop affects the expression of important protein markers in fat cells as well as in the hippocampus, which can worsen brain function and lead to neurodegeneration.

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Sweet! How glycogen is linked to heat generation in fat cells

Researchers describe how energy expenditure and heat production are regulated in obesity through a previously unknown cellular pathway.

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Sweet! How glycogen is linked to heat generation in fat cells

Researchers describe how energy expenditure and heat production are regulated in obesity through a previously unknown cellular pathway.

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Bone mineral density decreases less than expected after menopause

Bone mineral density at the femoral neck bone in postmenopausal women decreased by an average of 10% during a 25-year follow-up, according to a new study. Being the world's hitherto longest follow-up of changes in bone mineral density in postmenopausal women, the study shows that bone loss after menopause is significantly lower than has previously been assumed on the basis of earlier studies.

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Bone mineral density decreases less than expected after menopause

Bone mineral density at the femoral neck bone in postmenopausal women decreased by an average of 10% during a 25-year follow-up, according to a new study. Being the world's hitherto longest follow-up of changes in bone mineral density in postmenopausal women, the study shows that bone loss after menopause is significantly lower than has previously been assumed on the basis of earlier studies.

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A gut feeling: Understanding how our gut microbiome communicates with our immune system

An international team of scientists has identified a new connection between certain molecules produced by the microbiome and the function of a protein that impacts gut inflammation.

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A gut feeling: Understanding how our gut microbiome communicates with our immune system

An international team of scientists has identified a new connection between certain molecules produced by the microbiome and the function of a protein that impacts gut inflammation.

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A good night’s sleep may mitigate infant obesity risks

New research suggests that newborns who sleep longer and wake up less throughout the night are less likely to be overweight in infancy.

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A good night’s sleep may mitigate infant obesity risks

New research suggests that newborns who sleep longer and wake up less throughout the night are less likely to be overweight in infancy.

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Increased consumption of whole grains could significantly reduce the economic impact of type 2 diabetes

Increased consumption of whole grain foods could significantly reduce the incidence of type 2 diabetes and the costs associated with its treatment.

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Increased consumption of whole grains could significantly reduce the economic impact of type 2 diabetes

Increased consumption of whole grain foods could significantly reduce the incidence of type 2 diabetes and the costs associated with its treatment.

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How diet affects tumors

Researchers analyzed ketogenic and calorically restricted diets in mice, revealing how those diets affect cancer cells and offering an explanation for why restricting calories may slow tumor growth.

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How diet affects tumors

Researchers analyzed ketogenic and calorically restricted diets in mice, revealing how those diets affect cancer cells and offering an explanation for why restricting calories may slow tumor growth.

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A diet of essential amino acids could keep dementia at bay

Protein intake is known to be vital for maintaining brain function in older individuals. Now, using a mouse model of Alzheimer's disease, researchers have shown that the intake of a specific set of amino acids can inhibit the death of brain cells, protect the connections between them, and reduce inflammation, preserving brain function. Their research suggests that this amino acid combination called Amino LP7 can hinder the development of dementia, including Alzheimer's disease.

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A diet of essential amino acids could keep dementia at bay

Protein intake is known to be vital for maintaining brain function in older individuals. Now, using a mouse model of Alzheimer's disease, researchers have shown that the intake of a specific set of amino acids can inhibit the death of brain cells, protect the connections between them, and reduce inflammation, preserving brain function. Their research suggests that this amino acid combination called Amino LP7 can hinder the development of dementia, including Alzheimer's disease.

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Novel sugar detector system in the human mouth has implications for designing tastier, healthier beverages and foods

Scientists describe the first-in-human demonstration of a pathway that uses the sugar glucose, a component of table sugar and high fructose corn syrup, to signal the presence of calories, in addition to the well-studied sweet-taste receptor in taste buds.

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Novel sugar detector system in the human mouth has implications for designing tastier, healthier beverages and foods

Scientists describe the first-in-human demonstration of a pathway that uses the sugar glucose, a component of table sugar and high fructose corn syrup, to signal the presence of calories, in addition to the well-studied sweet-taste receptor in taste buds.

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Filling half of kids' plates with fruits and veggies helps increase consumption

Filling half of a child's plate with fruits and veggies isn't just recommended by the United States Dietary Guidelines, it also helps increase the amount of produce that kids end up eating, according to new research.

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Filling half of kids' plates with fruits and veggies helps increase consumption

Filling half of a child's plate with fruits and veggies isn't just recommended by the United States Dietary Guidelines, it also helps increase the amount of produce that kids end up eating, according to new research.

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Fasting is required to see the full benefit of calorie restriction in mice

Over the last few decades, scientists have discovered that long-term calorie restriction provides a wealth of benefits in animals. Researchers have largely assumed that reduced food intake drove these benefits by reprogramming metabolism. But a new study finds that reduced calorie intake alone is not enough; fasting is essential for mice to derive full benefit.

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Fasting is required to see the full benefit of calorie restriction in mice

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Americans are eating more ultra-processed foods

Consumption of ultra-processed foods has increased over the past two decades across nearly all segments of the U.S. population, according to a new study.

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Americans are eating more ultra-processed foods

Consumption of ultra-processed foods has increased over the past two decades across nearly all segments of the U.S. population, according to a new study.

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Key protein linked to appetite and obesity in mice

Researchers have identified a protein that plays a key role in how the brain regulates appetite and metabolism. Loss of the protein, XRN1, from the forebrain, resulted in obese mice with an insatiable appetite, according to a new study.

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Key protein linked to appetite and obesity in mice

Researchers have identified a protein that plays a key role in how the brain regulates appetite and metabolism. Loss of the protein, XRN1, from the forebrain, resulted in obese mice with an insatiable appetite, according to a new study.

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Contraceptive pill can reduce type 2 diabetes risk in women with polycystic ovary syndrome

A study has revealed for the first time that the contraceptive pill can reduce the risk of type 2 diabetes by over a quarter in women with polycystic ovary syndrome (PCOS). The research findings also show that women with PCOS have twice the risk of developing type 2 diabetes or pre-diabetes (dysglycemia) -- highlighting the urgent need to find treatments to reduce this risk.

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Contraceptive pill can reduce type 2 diabetes risk in women with polycystic ovary syndrome

A study has revealed for the first time that the contraceptive pill can reduce the risk of type 2 diabetes by over a quarter in women with polycystic ovary syndrome (PCOS). The research findings also show that women with PCOS have twice the risk of developing type 2 diabetes or pre-diabetes (dysglycemia) -- highlighting the urgent need to find treatments to reduce this risk.

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Scientists map brain circuit that drives activity in fertile females

Scientists have known for a century that female animals become more active just as they are about to ovulate, a behavior that evolved to enhance their chances of mating when they are fertile.

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Scientists map brain circuit that drives activity in fertile females

Scientists have known for a century that female animals become more active just as they are about to ovulate, a behavior that evolved to enhance their chances of mating when they are fertile.

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How highly processed foods harm memory in the aging brain

Four weeks on a diet of highly processed food led to a strong inflammatory response in the brains of aging rats that was accompanied by behavioral signs of memory loss, a new study has found. Researchers also found that supplementing the processed diet with the omega-3 fatty acid DHA prevented memory problems and reduced the inflammatory effects almost entirely in older rats.

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How highly processed foods harm memory in the aging brain

Four weeks on a diet of highly processed food led to a strong inflammatory response in the brains of aging rats that was accompanied by behavioral signs of memory loss, a new study has found. Researchers also found that supplementing the processed diet with the omega-3 fatty acid DHA prevented memory problems and reduced the inflammatory effects almost entirely in older rats.

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Early modern human from Southeast Asia adapted to a rainforest environment

Although there has been evidence of our species living in rainforest regions in Southeast Asia from at least 70,000 years ago, the poor preservation of organic material in these regions limits how much we know about their diet and ecological adaptations to these habitats. An international team of scientists has now applied a new method to investigate the diet of fossil humans: the analysis of stable zinc isotopes from tooth enamel. This method proves particularly helpful to learn whether prehistoric humans and animals were primarily eating meat or plants.

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Early modern human from Southeast Asia adapted to a rainforest environment

Although there has been evidence of our species living in rainforest regions in Southeast Asia from at least 70,000 years ago, the poor preservation of organic material in these regions limits how much we know about their diet and ecological adaptations to these habitats. An international team of scientists has now applied a new method to investigate the diet of fossil humans: the analysis of stable zinc isotopes from tooth enamel. This method proves particularly helpful to learn whether prehistoric humans and animals were primarily eating meat or plants.

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Higher fasting ‘hunger hormone’ levels from healthy diet may improve heart health and metabolism

Fasting levels of the 'hunger hormone' ghrelin rebound after weight loss and can help reduce belly fat and improve the body's sensitivity to insulin, according to a new study.

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Migraines caused by alterations in metabolite levels

Migraines are a pain in the head and in the hip pocket, but newly discovered genetic causes could lead the way to new preventative drugs and therapies.

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Higher fasting ‘hunger hormone’ levels from healthy diet may improve heart health and metabolism

Fasting levels of the 'hunger hormone' ghrelin rebound after weight loss and can help reduce belly fat and improve the body's sensitivity to insulin, according to a new study.

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Migraines caused by alterations in metabolite levels

Migraines are a pain in the head and in the hip pocket, but newly discovered genetic causes could lead the way to new preventative drugs and therapies.

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High BMI independently associated with death and longer ICU stay for COVID patients

In patients with COVID-19, a high body mass index (BMI) is associated with an increased risk of death and prolonged intensive care unit (ICU) stay, according to a new study.

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High BMI independently associated with death and longer ICU stay for COVID patients

In patients with COVID-19, a high body mass index (BMI) is associated with an increased risk of death and prolonged intensive care unit (ICU) stay, according to a new study.

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Rye a better choice than wheat for weight loss

Eating whole grain rye products instead of refined wheat alternatives can offer worthwhile health benefits. Researchers recently published a study showing that people who ate high-fiber products made from whole grain rye lost more body fat and overall weight than those who ate corresponding products made from refined wheat.

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Rye a better choice than wheat for weight loss

Eating whole grain rye products instead of refined wheat alternatives can offer worthwhile health benefits. Researchers recently published a study showing that people who ate high-fiber products made from whole grain rye lost more body fat and overall weight than those who ate corresponding products made from refined wheat.

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Research review shows intermittent fasting works for weight loss, health changes

Intermittent fasting can produce clinically significant weight loss as well as improve metabolic health in individuals with obesity, according to a new study.

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Research review shows intermittent fasting works for weight loss, health changes

Intermittent fasting can produce clinically significant weight loss as well as improve metabolic health in individuals with obesity, according to a new study.

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Is low-fat or whole-fat milk better for kids? Science says it makes no difference

A new study has found whole fat dairy is just as good for kids as low-fat.

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Is low-fat or whole-fat milk better for kids? Science says it makes no difference

A new study has found whole fat dairy is just as good for kids as low-fat.

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Winter-swimming Scandinavian men can teach us how the body adapts to extreme heat and cold

The Scandinavian winter swimming culture combines brief dips in cold water with hot sauna sessions -- and now, a study of young men who participate regularly in these polar plunges finds that winter swimming may allow the body to adapt to extreme temperatures. The findings suggest that routinely alternating swims or dips in chilly water with sauna sessions might affect how brown fat, also known as brown adipose tissue (BAT), burns energy and produces heat.

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